mpiBLAST:是一个基于MPI的NCBI BLAST的并行实现

　　官网：http://www.mpiblast.org/

　　mpiBLAST is a freely available, open-source, parallel implementation of NCBI BLAST. By efficiently utilizing distributed computational resources through database fragmentation, query segmentation, intelligent scheduling, and parallel I/O, mpiBLAST improves NCBI BLAST performance by several orders of magnitude while scaling to hundreds of processors. mpiBLAST is also portable across many different platforms and operating systems. Lastly, a renewed focus and consolidation of the many codebases has positioned mpiBLAST to continue to be of high utility to the bioinformatics community.

　　Key Features of mpiBLAST:

　　1. Database fragmentation

　　2.Query segmentation

　　3.Exact NCBI e-value scores

　　4. Increased per-query throughput

　　5.Improved query response time

　　6. Portable across all major operating systems

　　7. Integrated advanced job scheduling

　　8.Parallel input/output

　　9.Fault tolerant

　　10.High-performance on desktops, clusters, and HPC systems

　　mpiBLAST是一个基于MPI的NCBI BLAST的并行实现。它由代替formatdb 和 blastall的两个程序组成，在安装有MPI的并行计算机群集上执行BLAST作业。和传统BLAST相比，使用mpiBLAS有两个主要的好处。首先，mpiBLAST分割群集中每个节点上的数据库。由于数据库每个节点的分段越小，它就可以驻留在缓存存储器中，由于减少了磁盘I/O次数，从而大幅提高速度。其次，由于处理器相互间的通信需求低，所以它允许BLAST用户利用高效、低代价的Beowulf 群集。当数据库太大以至不能完全放在RAM中时，mpiBLAST 可以取得超线性的加速，而在一般情况下能获得线性的加速。